Bepc, Inc has an open position for a Research Associate II in South San Francisco, CA!!
W2 Contract 3 years
Pay and Benefits-$38-$44 an hour-Medical, Dental, Vision, Paid Life Insurance
We are seeking a highly motivated contractor to support discovery efforts in the Macrocycle Discovery Group within the Peptide Therapeutics Department.
The successful candidate will contribute to the identification of novel macrocyclic peptides using in vitro selection platforms and will play a key role in assay development, high-throughput screening, and data analysis for early drug discovery programs.
Key Responsibilities:
Conduct in vitro selection campaigns using mRNA and/or phage display technologies to discover active macrocyclic peptides targeting high-priority therapeutic proteins. Handle phage libraries, including amplification, titration, panning, and rescue procedures.
Design and execute ELISA-based binding assays for hit validation and screening. Utilize laboratory automation and high-throughput screening (HTS) techniques to enable efficient assay setup, sample processing, and reagent preparation.
Analyze next-generation sequencing (NGS) results using internal bioinformatics tools to identify early hits and guide selection campaign progression.
Test the incorporation and expression of non-canonical amino acid monomers to enhance library diversity through genetic code expansion. Maintain and manage complex reagent inventories used across multiple preclinical discovery platforms.
Collaborate cross-functionally with scientists in biochemistry, screening, and informatics to support project goals and timelines.
Qualifications:
B.S., M.S., or equivalent degree in Biochemistry, Molecular Biology, Chemical Biology, or a related discipline with relevant lab-based experience.
Hands-on experience with in vitro display technologies, particularly mRNA display and/or phage display (including phage propagation and selection).
Proficiency in ELISA, western blot, and high-throughput screening methods.
Familiarity with NGS data analysis and experience with laboratory automation platforms.
Strong attention to detail, excellent organizational skills, and ability to work both independently and as part of a collaborative team.
...Precision Oral Surgery - Loveland, CO Dental Assistant Oral Surgery Surgical Assistant Oral Surgery Position Highlights... ...: Step into the fast-paced world of oral surgery as an Oral Surgeon Surgical Assistant! Your role is pivotal, aiding surgeons with...
...A key client of Appleton Finn is looking for an electrical estimator in the Fresno area. This position involves preparing detailed cost estimates, submitting bids, drafting segments of contract proposals, and engaging with clients, vendors, engineers, architects, building...
...enjoys helping others? New Gateways, Inc. is hiring Direct Care Professionals to support adults with Intellectual and Developmental Disabilities. In this... ...able to lift 50 lbs and remain active throughout the day. Comfort with providing personal care to adults is also essential...
...The LHH is seeking an Environment, Health and Safety Coordinator (EHS Coordinator) for a Direct Hire, Permanent Placement position with a manufacturing client located in the Lafayette, IN Area. This is an opportunity to join an established EHS Department which a strong...
...in a range of industries from Industrial/Manufacturing, Healthcare, Data Center, Aviation to Commercial Real Estate needs an Accounts Payable Specialist that works well independently and within a team. NO HYBRID OR REMOTE OPPORTUNITY - ONSITE ONLY Job Description...